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Found 2 Enz. Inhib. hit(s) with Target = 'Phospholipase D' and Ligand = 'BDBM123757'
TargetPhospholipase D(Streptomyces chromofuscus)
Roxbury Community College

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)
Affinity DataIC50:  150nMpH: 8.0Assay Description:A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D(Streptomyces sp. PMF)
University of Massachusetts Boston

LigandPNGBDBM123757(1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...)
Affinity DataIC50:  1.20E+3nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed