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Found 3 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM455026'
TargetPlasma kallikrein(Homo sapiens (Human))
Shire Human Genetic Therapies

US Patent
LigandPNGBDBM455026(US10730874, Compound I-50 | US10730874, Compound I...)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Shire Human Genetic Therapies

US Patent
LigandPNGBDBM455026(US10730874, Compound I-50 | US10730874, Compound I...)
Affinity DataEC50:  5.5nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Shire Human Genetic Therapies

US Patent
LigandPNGBDBM455026(US10730874, Compound I-50 | US10730874, Compound I...)
Affinity DataEC50:  5.5nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent