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Found 3 Enz. Inhib. hit(s) with Target = 'Plasmepsin II' and Ligand = 'BDBM233141'
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50:  1.05E+3nMpH: 5.0Assay Description:The assay was performed with plasmepsin-II/cathepsin D (1.2 nM) and substrate (malaria FRET-1; 1.0 μM) in 0.1 M sodium acetate buffer pH 5, contai...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM233141(1,2-Diphenylhydrazine | Mr-II-10)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of recombinant Plasmodium falciparum Plasmepsin 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed