Found 12 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor beta' and Ligand = 'BDBM13530' TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 50nMAssay Description:Inhibition of PDGFR phosphorylation in BALB/c mouse 3T3 by Western blot analysisMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 72nMAssay Description:Inhibition of PDGFRbeta autophosphorylation in human A31 cells by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Rattus norvegicus)
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Novartis Institutes Of Biomedical Research (Nibr)
Curated by ChEMBL
Affinity DataIC50: 162nMAssay Description:Inhibition of PDGFR-beta driven proliferation of rat A10 cells after 68 hrs in presence of rat recombinant PDGF-BB by cell titer-glo luminescence ass...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 240nMAssay Description:Inhibition of wild type Platelet-derived growth factor receptor beta phosphorylation in CHO cellsMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 240nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by liquid scintillation countingMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 386nMAssay Description:Inhibition of PDGFRbeta kinaseMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataIC50: 607nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataKd: 28nMAssay Description:Average Binding Constant for PDGFRB; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataKd: 14nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataKd: 14nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Genomics Institute of The Novartis Research Foundation
Curated by PDSP Ki Database
Affinity DataKd: 14nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair
