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Found 2 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM421584'
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM421584(3-[5-(difluoromethyl)-1,3,4-thiadiazol-2-yl]-6-flu...)
Affinity DataIC50: >1.50E+5nMAssay Description:PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM421584(3-[5-(difluoromethyl)-1,3,4-thiadiazol-2-yl]-6-flu...)
Affinity DataIC50: >1.50E+5nMAssay Description:PARP1 In vitro selectivity assays were conducted as a 10 ul reaction volume in a NUNC Maxisorp 384-well assay plate pre-coated in-house with Histones...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent