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Found 4 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 2' and Ligand = 'BDBM207600'
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207600(US10501467, Example 45 | US9260440, 45 | US9617273...)
Affinity DataIC50:  0.800nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207600(US10501467, Example 45 | US9260440, 45 | US9617273...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of PARP-2 (unknown origin) pre-incubated for 30 mins before addition of activated DNA and NAD by chemiluminescent assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207600(US10501467, Example 45 | US9260440, 45 | US9617273...)
Affinity DataIC50:  800nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207600(US10501467, Example 45 | US9260440, 45 | US9617273...)
Affinity DataIC50:  800nMAssay Description:PARP-2 and PARP-3 enzymatic assays were conducted using commercial PARP-2/PARP-3 Chemiluminescent Assay Kit (BPS Biosciences) and the protocols with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent