Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM50007583'
TargetPoly [ADP-ribose] polymerase tankyrase-1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50007583(CHEBI:62882 | CHEMBL562310)
Affinity DataIC50:  131nMAssay Description:Inhibition of TNKS-1 in mouse L-Wnt-STF cells assessed as disruption of Wnt signaling after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50007583(CHEBI:62882 | CHEMBL562310)
Affinity DataIC50:  131nMAssay Description:Antagonistic activity against histamine H3 receptor in guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50007583(CHEBI:62882 | CHEMBL562310)
Affinity DataIC50:  131nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed