Found 50 Enz. Inhib. hit(s) with Target = 'Polyamine deacetylase HDAC10' and Ligand = 'BDBM19149' TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of human recombinant HDAC10 using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC substrate incubated for 15 to 30 minsMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Competitive inhibition of HDAC10 using KI-104 as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using fluorogenic HDAC substrate 3 ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 29.1nMpH: 7.5Assay Description:Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using Ac-peptide-AMC as substrate incubated for 240 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant HDAC10 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate by measuring fluorescence intensity incubated for 30 mins by micropl...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC10 expressed in baculovirus infected Sf9 insect cells using Ac-Arg-His-Lys(Ac)-Lys(Ac)-AMC ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant human HDAC10 using Fluor-de-Lys as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant HDAC10More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of HDAC10 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of HDAC10 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC10 (1 to 481 residues) using Arg-His-Lys-Lys(Ac) substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged HDAC10 (2 to 631 residues) expressed in baculovirus infected using 7-AMC-labelled HDAC substra...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC10 (unknown origin) using Ac-ArgThr- Lys(Ac)Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:In vitro antagonistic activity against kinin-induced rabbit jugular vein contraction.More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of HDAC10 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of HDAC10 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant his-tagged human HDAC10 using Ac-ArgHisLys (Ac) Lys (Ac)-AMC substrate preincubated for 5 mins followed by substrate additi...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human HDAC10 using ArgHisLysLys(Ac) fluorogenic peptide as a substrate by fluorimetric assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 159nMAssay Description:Inhibition of HDAC10 (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human HDAC10 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substra...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC10 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of tubastatin-Alexa647-tracer binding to recombinant GST-tagged HDAC10 (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 208nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 238nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 278nMAssay Description:Inhibition of HDAC10 (unknown origin) using biotinylated histone H3 KAc peptide (1 to 21 residues) as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC10 (unknown origin) using RHKK(Ac) fluorogenic acetylated peptide substrate by fluorometric assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 432nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 456nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 456nMAssay Description:Inhibition of human HDAC10 by fluorimetric assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 456nMAssay Description:Inhibition of human HDAC-10 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 456nMAssay Description:Inhibition of human HDAC-10 using RHKK(Ac) as substrate by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 456nMAssay Description:Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 456nMAssay Description:Inhibition of human HDAC10 using RHKK(Ac) as substrate by fluorimetric analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 459nMAssay Description:Inhibition of human HDAC10 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of human HDAC10 using RHK-K(Ac)-AMC as substrate incubated for 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 604nMAssay Description: I. Compound handling: Testing compounds were dissolved in 100% DMSO to a specific concentration. The serial dilution was conducted by epMotion 5070 ...More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 686nMAssay Description:Inhibition of recombinant human HDAC10 after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 686nMAssay Description:Inhibition of human recombinant HDAC10 after 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 982nMAssay Description:Inhibition of HDAC 10 in human HeLa nuclear extract measured after 60 mins by fluorometric analysisMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Technical University Of Denmark
Curated by ChEMBL
Technical University Of Denmark
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of dye-labeled tracer binding to HDAC10 (unknown origin) transfected in human HeLa cells measured after 2 hrs by nano-luciferase reporter ...More data for this Ligand-Target Pair
