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Found 3 Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 1' and Ligand = 'BDBM50031467'
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.50E+4nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Pierre Fabre Dermo-Cosmetique

US Patent
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  2.90E+4nMAssay Description:A tyrosinase inhibition assay was carried out using the method reported by Jones et al. (2002) Pigment. Cell Res. 15:335. Using this method, the conv...More data for this Ligand-Target Pair
In DepthDetails US Patent