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Found 9 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM17638'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase in Human whole blood (HWBL) stimulated with calcium ionophore (A23187) and LTB4 measured by enzyme immunoa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against 5-lipoxygenase catalysis (5-LO) in sonicated rat basophilic leukemia cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity of the compound against 5-lipoxygenase of RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 5-lipoxygenase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was evaluated for its inhibitory activity against 5-LO(5-lipoxygenase) in intact RBL-1 cell line assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of rat basophilic leukemia cell 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50: >2.50E+5nMAssay Description:Tested for its inhibitory activity against 5-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  3.70E+6nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed