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Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50008997'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008997(1-Methyl-1,2-dihydro-indazol-3-one | CHEMBL412905)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008997(1-Methyl-1,2-dihydro-indazol-3-one | CHEMBL412905)
Affinity DataEC50: >6.74E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed