Found 6 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50008999' 
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of [14C]-arachidonic acid conversion to 5-HETE by broken cell 5-LO isolated from guinea pig PMNMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre De Recherches De Vitry
Curated by ChEMBL
Centre De Recherches De Vitry
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Iin vitro inhibition of 5-lipoxygenase activity in rat basophil leukemia type 1(RBL1) cell homogenates, (reduction of [14C]-5-HETE formation)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre De Recherches De Vitry
Curated by ChEMBL
Centre De Recherches De Vitry
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre De Recherches De Vitry
Curated by ChEMBL
Centre De Recherches De Vitry
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of 5-lipoxygenase in rat (peritoneal assay)More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Centre De Recherches De Vitry
Curated by ChEMBL
Centre De Recherches De Vitry
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
Affinity DataEC50: >3.72E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
