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Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50009002'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009002(2-Methyl-1,2-dihydro-indazol-3-one | CHEMBL3144583)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of LTB4 (LT) production in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009002(2-Methyl-1,2-dihydro-indazol-3-one | CHEMBL3144583)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009002(2-Methyl-1,2-dihydro-indazol-3-one | CHEMBL3144583)
Affinity DataEC50:  6.74E+3nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed