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Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50045663'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045663(4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50:  12nMAssay Description:In vitro inhibition of LTB4 biosynthesis in [Ca2+]-ionophore-activated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50045663(4-[1-(4-Chloro-benzyl)-4-methyl-6-(5-phenyl-pyridi...)
Affinity DataIC50:  20nMAssay Description:In vitro test for inhibition of 5-lipoxygenase in cell-free preparations from rat PMN leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed