Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50116905' TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human 5-LOX expressed in Escherichia coli Bl21 (DE3) assessed as reduction in LTB4 and 5-H(P)ETE) formation pre-incubated for 10 mins b...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Ferrara
Curated by ChEMBL
University Of Ferrara
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-LOX in human neutrophils assessed as reduction in LTB4 and 5-H(P)ETE) formation pre-incubated for 15 mins before A23187 and arachidon...More data for this Ligand-Target Pair
