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Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50331797'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331797(1-(3-phenyl-6-((4-(1,1,1-trifluoro-2-hydroxybutan-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant 5-lipoxygenase assessed as arachidonic acid oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331797(1-(3-phenyl-6-((4-(1,1,1-trifluoro-2-hydroxybutan-...)
Affinity DataIC50:  84nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed