Found 2 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50561492' TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt
Curated by ChEMBL
Goethe-University Of Frankfurt
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of 5-LOX (unknown origin) expressed in Escherichia coli BL21-(DE3) pre-incubated for 15 mins before AA substrate addition and measured aft...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Of Frankfurt
Curated by ChEMBL
Goethe-University Of Frankfurt
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in 5-HETE and LTB4 formation pre-incubated for 15 mins before addition of AA and A23187 and m...More data for this Ligand-Target Pair
