Report error Found 13 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM7460'
Affinity DataEC50: >3.30E+5nMAssay Description:Ex vivo inhibition of LTB4 production was measured in dog bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-lipoxygenase (5-lo) in intact rat polymorphonuclear leukocyte RPMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Compound was tested for its in vitro inhibitory activity against RBL-1 5-LO (time dependent)More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Iin vitro inhibition of 5-lipoxygenase activity in rat basophil leukemia type 1(RBL1) cell homogenates, (reduction of [14C]-5-HETE formation)More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of 5-lipoxygenase in rat (peritoneal assay)More data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Inhibition of 5LOX in human PBMC by EIA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 5-LOX in polymorphonuclear leucocytes (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.34E+3nMAssay Description:Inhibition of 5-LOX (unknown origin) by colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in human neutrophils using arachidonic acid as substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of LTB4 production was measured in rat bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human PMNL 5-LOX using arachidonic acid as substrate after 5 mins by HPLC methodMore data for this Ligand-Target Pair
