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Found 3 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX12' and Ligand = 'BDBM50447220'
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447220(CHEMBL3113170 | US10752581, Compound 50)
Affinity DataIC50:  330nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447220(CHEMBL3113170 | US10752581, Compound 50)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Eastern Virginia Medical School

US Patent
LigandPNGBDBM50447220(CHEMBL3113170 | US10752581, Compound 50)
Affinity DataIC50:  2.70E+3nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In DepthDetails US Patent