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Found 4 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50112179'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:The hERG inhibition study aims at quantifying the in vitro effects of compounds of the invention on the potassium-selective IKr current generated in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
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US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (Igr) which is involved in car...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (IKr) which is involved in car...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM50112179(CHEMBL3608740 | US10030025, Compound 20 | US108367...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed