Found 4 Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM193081' 
Affinity DataIC50: 6.20nMAssay Description:Inhibition of gamma secretase derived from human Hela cell membrane assessed as reduction in amyloid beta (1 to 40) production by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.84nMT: 2°CAssay Description:The ability of compounds to modulate production of amyloid beta protein
Abeta(1-42) was determined using human WT-APP overexpressing CHO cells.
Cel...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of gamma-secretase (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Modulation of gamma-secretase in CHO cells expressing human APP assessed as reduction in amyloid beta (1 to 42 residues) production after 24 hrs by E...More data for this Ligand-Target Pair
