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Found 4 Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50118691'
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at progesterone receptor expressed in T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed