Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Progesterone receptor' and Ligand = 'BDBM50144435'
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144435(1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...)
Affinity DataIC50:  3.30nMAssay Description:Displacement of [3H]R5020 from human PR in human T47D cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144435(1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...)
Affinity DataIC50: >3.00E+3nMAssay Description:Ability to block progesterone induced alkaline phosphatase activity in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144435(1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human PR expressed in human T47D cells assessed as stimulation of alkaline phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50144435(1-methyl-5-[2'-oxospiro[cyclohexane-1,3'-(2',3'-di...)
Affinity DataEC50:  2.80nMAssay Description:Agonistic activity measures the ability to induce alkaline phosphatase in T47D human breast cancer cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed