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Found 4 Enz. Inhib. hit(s) with Target = 'Prolyl 4-hydroxylase subunit alpha-1' and Ligand = 'BDBM26114'
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataKi:  800nMAssay Description:Inhibitory activity against prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataKi:  2.60E+3nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Rattus norvegicus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataIC50:  5.18E+3nMAssay Description:Compound was evaluated for the inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)
Affinity DataIC50:  1.50E+4nMpH: 7.8Assay Description:Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed