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Found 3 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase FAP' and Ligand = 'BDBM50382283'
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50382283(CHEMBL2022530 | US9346814, Ref. Cmpd No 1 (Example...)
Affinity DataKi:  110nMAssay Description:Inhibition of FAP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp

US Patent
LigandPNGBDBM50382283(CHEMBL2022530 | US9346814, Ref. Cmpd No 1 (Example...)
Affinity DataIC50:  110nMpH: 8.3 T: 2°CAssay Description:Enzyme activities were determined kinetically in a final volume of 200 μl for 10 minutes at 37° C. by measuring the initial velocities of pNA ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Mus musculus (Mouse))
Universiteit Antwerp

US Patent
LigandPNGBDBM50382283(CHEMBL2022530 | US9346814, Ref. Cmpd No 1 (Example...)
Affinity DataIC50:  110nMAssay Description:Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed