Found 5 Enz. Inhib. hit(s) with Target = 'Prolyl endopeptidase FAP' and Ligand = 'BDBM622251' 
Affinity DataIC50: 0.100nMAssay Description:Table 1: Compounds were tested in a biochemical inhibition assay using hFAP enzyme at 0.24 nM FAC (Proteros, 38-760 (PR-0071)) and the substrate Ala-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Table 1: Compounds were tested in a direct binding assay using 8K surface plasmon resonance biosensor (GE Healthcare) at 20° C. Immobilization of hFA...More data for this Ligand-Target Pair
Affinity DataKoff: 5.90E+6s-1Assay Description:Table 1: Compounds were tested in a direct binding assay using 8K surface plasmon resonance biosensor (GE Healthcare) at 20° C. Immobilization of hFA...More data for this Ligand-Target Pair
Affinity DataKon: 0.000200M-1s-1Assay Description:Table 1: Compounds were tested in a direct binding assay using 8K surface plasmon resonance biosensor (GE Healthcare) at 20° C. Immobilization of hFA...More data for this Ligand-Target Pair
Affinity DataKd: 0.0490nMAssay Description:Table 1: Compounds were tested in a biochemical inhibition assay using human Fibroblast activation protein alpha (hFAP) enzyme at 2.4 pM FAC (Protero...More data for this Ligand-Target Pair
