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Found 2 Enz. Inhib. hit(s) with Target = 'Prolyl hydroxylase EGLN3' and Ligand = 'BDBM50446906'
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446906(CHEMBL3115290)
Affinity DataIC50:  1nMAssay Description:Inhibition of 6His-tagged PHD3 (1 to 239) (unknown origin)-mediated Cy5CODD hydroxylation expressed in Escherichia coli preincubated for 3 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Janssen Research And Development

Curated by ChEMBL
LigandPNGBDBM50446906(CHEMBL3115290)
Affinity DataEC50:  100nMAssay Description:Inhibition of PHD3 in human Hep3B cells assessed as stimulation of EPO release after 48 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed