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Found 1 Enz. Inhib. hit(s) with Target = 'Proprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor' and Ligand = 'BDBM586427'
TargetProprotein convertase subtilisin/kexin type 9/Low-density lipoprotein receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM586427(US11530244, Compound 424)
Affinity DataIC50:  50nMAssay Description:The PCSK9 Alexa FRET Standard assay measured the interaction between PCSK9 and an AlexaFluor647 (AF) tagged cyclic peptide, Reagent A (KD=83 nM). A s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent