Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Proprotein convertase subtilisin/kexin type 9' and Ligand = 'BDBM200362'
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200362(US9227956, 46 | US9227956, 47)
Affinity DataIC50:  4.67E+3nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200362(US9227956, 46 | US9227956, 47)
Affinity DataIC50: >2.00E+4nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200362(US9227956, 46 | US9227956, 47)
Affinity DataIC50: >2.00E+4nMAssay Description:An in-vitro AlphaLISA assay (Perkin Elmer) was developed in order to quantitate the level of PCSK9 secreted into the cell culture media following com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM200362(US9227956, 46 | US9227956, 47)
Affinity DataIC50:  3.34E+4nMAssay Description:In order to eliminate the permeability barrier inherent to the WT7 and SCHH cell-based assays a cell-free system was also established to access compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent