Affinity DataKi: 68nMAssay Description:Binding affinity towards human CRTH2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Concentration required to inhibit PGD-2 induced chemotaxis of Th2 cells expressing CRTH2More data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Concentration required to inhibit PGD-2 induced change in the shape of human eosinophils expressing CRTH2More data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Concentration required to inhibit PGD-2 (10 nM) stimulated [Ca2+] flux in CHO cells expressing human CRTH2 receptorMore data for this Ligand-Target Pair