Affinity DataKi: 13nMAssay Description:Antagonistic activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced calcium mobilization after 60 mins by Fluo-3 based fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CRTH2 expressed in Th2 cells assessed as inhibition of PGD2-induced IL13 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Antagonist activity at CRTH2 expressed in Th2 cells assessed as inhibition of PGD2-induced chemotaxisMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Antagonist activity at CRTH2 expressed in Th2 cells assessed as inhibition of PGD2-induced antiapoptotic activityMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Displacement of [3H]PGD2 from human prostaglandin D2 receptor in presence of human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of CRTH2 in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding preinc...More data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Antagonist activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced shape changeMore data for this Ligand-Target Pair