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Found 5 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1/2' and Ligand = 'BDBM50009004'
TargetProstaglandin G/H synthase 1/2(RAT)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibition of PGE-2 production was measured in rat bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1/2(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  6.90E+3nMAssay Description:Compound was evaluated for inhibition against cyclooxygenase of bovine seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against human whole blood, TXB2 cyclooxygenase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibitory activity of the compound against human whole blood, LTB4 5-lipoxygenase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50009004((phenidone)1-Phenyl-pyrazolidin-3-one | 1-Phenyl-p...)
Affinity DataIC50:  9.40E+4nMAssay Description:Inhibitory activity of the compound against intact human PMNL, LTB4 5-lipoxygenase was evaluatedMore data for this Ligand-Target Pair
In DepthDetails Article