Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM23416'
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23416BDBM23416((+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihyd...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23416BDBM23416((+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihyd...)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Pennsylvania School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23416BDBM23416((+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihyd...)
Affinity DataKd:  4.07E+4nMAssay Description:Binding affinity to COX1 in sheep seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23416BDBM23416((+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihyd...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of bovine seminal vesicle microsomal COX1-mediated prostaglandin productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed