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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 1' and Ligand = 'BDBM50057518'
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057518(4-(5-Phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzen...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Searle Research And Development

Curated by ChEMBL
LigandPNGBDBM50057518(4-(5-Phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzen...)
Affinity DataIC50:  5.51E+4nMAssay Description:In vitro inhibitory concentration required to block recombinant human prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057518(4-(5-Phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzen...)
Affinity DataIC50:  2.13E+5nMAssay Description:Inhibition of purified ovine COX-1 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed