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Found 4 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM17636'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50:  16nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50:  16nMAssay Description:Inhibition of COX2 expressed in baculovirus infected SF-21 cells assessed as formation of PGH2 from PGG2 using arachidonic acid as substrate preincub...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

US Patent
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair