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Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM185732'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rottapharm Biotech

US Patent
LigandPNGBDBM185732(US9162979, 27-II)
Affinity DataIC50:  14nMT: 2°CAssay Description:The murine monocyte/macrophage cell line J774 is grown in Dulbecco's modified Eagle's medium (DMEM), enriched with glutamine (2 mM), HEPES (25 mM), p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM185732(US9162979, 27-II)
Affinity DataIC50:  45nMAssay Description:Inhibition of LPS-induced COX-2 in mouse J774 cells using arachidonic acid as substrate assessed as inhibition of prostaglandin E2 production preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed