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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50273683'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273683(2-(4,6-Diphenethoxypyrimidin-2-ylthio)hexanoic aci...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273683(2-(4,6-Diphenethoxypyrimidin-2-ylthio)hexanoic aci...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant COX2 after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50273683(2-(4,6-Diphenethoxypyrimidin-2-ylthio)hexanoic aci...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as residual activity by measuring formation of 12-HHT from arachidonic acid by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed