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Found 3 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-9' and Ligand = 'BDBM50573691'
TargetProteasome subunit beta type-9(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50573691(CHEMBL4845896)
Affinity DataIC50:  28nMAssay Description:Inhibition of human 20S proteasome LMP2 activity in human RPMI-8226 cells using Ac-PAL-AMC as fluorogenic substrate incubated for 72 hrs by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50573691(CHEMBL4845896)
Affinity DataIC50:  158nMAssay Description:Inhibition of human 20S proteasome LMP2 using Ac-PAL-AMC as fluorogenic substrate measured every minute for 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50573691(CHEMBL4845896)
Affinity DataIC50:  204nMAssay Description:Inhibition of human 20S proteasome LMP2 activity in human RPMI-8226 cells overexpressing ABCB1 using Ac-PAL-AMC as fluorogenic substrate incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed