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Found 2 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 5' and Ligand = 'BDBM336999'
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM336999(US9745291, Compound 269 | US9745291, Compound 45 |...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PRMT5 in human Z138 cells assessed as reduction in symmetrical dimethylation of arginine containing substrate using SmD3 as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM336999(US9745291, Compound 269 | US9745291, Compound 45 |...)
Affinity DataIC50: <100nMAssay Description:Molecular Biology: Full-length human PRMT5 (NM_006109.3) transcript variant 1 clone was amplified from a fetal brain cDNA library, incorporating flan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB