Found 4 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50481615' TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Binding affinity to FPP site of human recombinant FTase by competitive Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Affinity DataKi: 1.50E+4nMAssay Description:Binding affinity to CaaX site of human recombinant FTase by non-competitive Michaelis-Menten analysis for enzyme-substrate-inhibitor complexMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Binding affinity to CaaX site of human recombinant FTase by non-competitive Michaelis-Menten analysis for enzyme-inhibitor complexMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair
