Found 2 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50481625'
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Binding affinity to FPP site of human recombinant FTase by competitive Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Centre De Recherche De Gif-Sur-Yvette
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant FTase by fluorescent-based assayMore data for this Ligand-Target Pair