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Found 3 Enz. Inhib. hit(s) with Target = 'Protein kinase C zeta type' and Ligand = 'BDBM139466'
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM139466(US8889672, 317-094-001)
Affinity DataIC50:  2.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM139466(US8889672, 317-094-001)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM139466(US8889672, 317-094-001)
Affinity DataEC50:  1nMAssay Description:Inhibition of atypical PKCzeta in HEK293 cells assessed as TNF-induced NFkappaB activation incubated for 3 hrs prior to TNF induction measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed