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Found 2 Enz. Inhib. hit(s) with Target = 'Protein polybromo-1' and Ligand = 'BDBM342597'
TargetProtein polybromo-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity to His-tagged BRD4 BD1-BD2 (K57 to K550 residues) (unknown origin) after 1 hr by Alexa-647-conjugated probe based TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProtein polybromo-1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM342597(N-[3-(3-methyl-4-oxo-4,5,6,7-tetrahydro-2H-isoindo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PBRM1 bromodomain 2 (S178 to E291 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed