Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Protein-lysine 6-oxidase' and Ligand = 'BDBM50232678'
TargetProtein-lysine 6-oxidase(Human)
Pharmakea

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232678BDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 550nMAssay Description:Inhibition of full length recombinant human LOX expressed in HEK cells assessed as reduction in H2O2 production using DAP as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Human)
Pharmakea

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232678BDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Bovine)
Pharmaxis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232678BDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Bovine)
Pharmaxis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232678BDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 1.00E+4nMAssay Description:Lysyl oxidase (LOX) is an extracellular copper dependent enzyme which oxidizes peptidyl lysine and hydroxylysine residues in collagen and lysine resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2025
Entry Details
US Patent

TargetProtein-lysine 6-oxidase(Human)
Pharmakea

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232678BDBM50232678(CHEBI:27413 | CHEMBL1618272 | US10717734, Compound...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed