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Found 2 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50197614'
TargetProteinase-activated receptor 1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50197614(CHEMBL3939323 | US10322140, Example 12)
Affinity DataIC50:  0.990nMAssay Description:Frozen HEK 293 Cells were plated in 384-well PDL coated plates at 12000 cells/well in 50 uL of DMEM media containing 10% FBS, pen/strep/L-Glutamine a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProteinase-activated receptor 1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM50197614(CHEMBL3939323 | US10322140, Example 12)
Affinity DataIC50:  0.990nMAssay Description:Antagonist activity at PAR-1 in HEK293 cells incubated for 30 mins followed by Ala-parafluoroPhe-Arg-Cha-Cit-Try-NH2 substrate addition by calcium-5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed