Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 2' and Ligand = 'BDBM429556'
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429556((2-(3- Azabicyclo[3.1.0] hexan-3-yl)-4- fluorophen...)
Affinity DataIC50:  4.67E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429556((2-(3- Azabicyclo[3.1.0] hexan-3-yl)-4- fluorophen...)
Affinity DataIC50:  4.67E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429556((2-(3- Azabicyclo[3.1.0] hexan-3-yl)-4- fluorophen...)
Affinity DataIC50:  1.16E+4nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429556((2-(3- Azabicyclo[3.1.0] hexan-3-yl)-4- fluorophen...)
Affinity DataIC50:  1.16E+4nMAssay Description:Calcium mobilization was measured using 1321N1 cells stably expressing human PAR2. Cells were seeded in 384-well plates at 4,000 cells per well in 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent