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Found 1 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM14078'
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14078((2S)-1-(2-amino-2,2-diphenylacetyl)-N-[1-(1,3-benz...)
Affinity DataKi:  2.10nM ΔG°:  -51.5kJ/mole IC50:  15nMpH: 7.4 T: 2°CAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed