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Found 2 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM14137'
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14137(2-ketobenzothiazole 75 | methyl (3S)-4-[(2S)-2-{[(...)
Affinity DataKi:  1.40nM IC50:  56nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14137(2-ketobenzothiazole 75 | methyl (3S)-4-[(2S)-2-{[(...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed