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Found 2 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase ROS' and Ligand = 'BDBM50062371'
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50062371(CHEMBL3397292)
Affinity DataIC50:  478nMAssay Description:Inhibition of ROS1 (unknown origin) incubated for 20 mins followed by [33P]ATP addition measured after 120 mins by HotSpot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Korea University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50062371(CHEMBL3397292)
Affinity DataIC50:  9.09E+4nMAssay Description:Inhibition of ROS1 in human HCC78 cells after 48 hrs by CellTitre-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed