Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50097973'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50097973(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  25.1nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50097973(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  27nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097973(2-(4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50:  1.40E+3nMAssay Description:Concentration required for inhibition of c-Src mediated phosphorylation of Fak in IC8.1 fibroblast cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed